Immunotoxicology in the pharmaceutical industry.
نویسنده
چکیده
Development of an immunotoxicology program within the pharmaceutical industry is described. With few guidelines in the area and a multitude of factors to consider, a basic screen for evaluating immune competence in species routinely used in toxicologic studies has been proposed. The future of immunotoxicology depends upon the ability of the selected immune function tests to be predictive of human risk.
منابع مشابه
Species differences in the structure and function of the immune system.
With the recent publication of regulatory guidelines from both the FDA and the CPMP addressing the investigation of immunotoxicity of new chemical entities has come the requisite increased application of immunotoxicology protocols. Importantly, the fulfillment of these protocols may require the use of different species, and while in many cases information concerning the structure and function o...
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عنوان ژورنال:
- Environmental Health Perspectives
دوره 43 شماره
صفحات -
تاریخ انتشار 1982